Earth 2160 follows the progress of the factions, the United Civilized States, the Eurasian Dynasty and the Lunar Corporation, who, after escaping the doomed Earth, headed for Mars. After a time of relative peace and recovery, the factions once again come to blows, with a fourth faction of extraterrestrial nature, named the Morphidians, coming into play. Just a few thousand humans were specifically chosen for the evacuation of Earth, and as such manpower and resources are limited.